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Cyclophilin D as a potential therapeutic target of liver ischemia/reperfusion injury by mediating crosstalk between apoptosis and autophagy

BACKGROUND: Liver ischemia/reperfusion (I/R) injury is a complex and multifactorial pathophysiological process. It is well recognized that the membrane permeability transition pore (mPTP) opening of mitochondria plays a crucial role in cell death after I/R injury. Cyclophilin D (CypD) is a critical...

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Detalles Bibliográficos
Autores principales: Yang, Mengjiao, Wang, Zhihui, Xie, Jin, Reyad‐ul‐Ferdous, Md., Li, Siying, Song, Yongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497823/
https://www.ncbi.nlm.nih.gov/pubmed/37711863
http://dx.doi.org/10.1002/cdt3.78