Pyrroloquinoline quinone alleviates natural aging‐related osteoporosis via a novel MCM3‐Keap1‐Nrf2 axis‐mediated stress response and Fbn1 upregulation

Age‐related osteoporosis is associated with increased oxidative stress and cellular senescence. Pyrroloquinoline quinone (PQQ) is a water‐soluble vitamin‐like compound that has strong antioxidant capacity; however, the effect and underlying mechanism of PQQ on aging‐related osteoporosis remain uncle...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jie, Zhang, Jing, Xue, Qi, Liu, Boyang, Qin, Ran, Li, Yiping, Qiu, Yue, Wang, Rong, Goltzman, David, Miao, Dengshun, Yang, Renlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497824/
https://www.ncbi.nlm.nih.gov/pubmed/37365714
http://dx.doi.org/10.1111/acel.13912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497824/
https://www.ncbi.nlm.nih.gov/pubmed/37365714
http://dx.doi.org/10.1111/acel.13912

Ejemplares similares