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Pyrroloquinoline quinone alleviates natural aging‐related osteoporosis via a novel MCM3‐Keap1‐Nrf2 axis‐mediated stress response and Fbn1 upregulation
Age‐related osteoporosis is associated with increased oxidative stress and cellular senescence. Pyrroloquinoline quinone (PQQ) is a water‐soluble vitamin‐like compound that has strong antioxidant capacity; however, the effect and underlying mechanism of PQQ on aging‐related osteoporosis remain uncle...
Autores principales: | Li, Jie, Zhang, Jing, Xue, Qi, Liu, Boyang, Qin, Ran, Li, Yiping, Qiu, Yue, Wang, Rong, Goltzman, David, Miao, Dengshun, Yang, Renlei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497824/ https://www.ncbi.nlm.nih.gov/pubmed/37365714 http://dx.doi.org/10.1111/acel.13912 |
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