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Deletion of enzymes for de novo NAD (+) biosynthesis accelerated ovarian aging

Recent advances highlight the pivotal role of nicotinamide adenine dinucleotide (NAD(+)) in ovarian aging. However, the roles of de novo NAD(+) biosynthesis on ovarian aging are still unknown. Here, we found that genetic ablation of Ido1 (indoleamine‐2,3‐dioxygenase 1) or Qprt (Quinolinate phosphori...

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Detalles Bibliográficos
Autores principales: Yang, Qingling, Li, Hui, Wang, Huan, Chen, Wenhui, Zeng, Xinxin, Luo, Xiaoyan, Xu, Jianmin, Sun, Yingpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497836/
https://www.ncbi.nlm.nih.gov/pubmed/37332134
http://dx.doi.org/10.1111/acel.13904