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Astrocyte‐ and NMDA receptor‐dependent slow inward currents differently contribute to synaptic plasticity in an age‐dependent manner in mouse and human neocortex

Slow inward currents (SICs) are known as excitatory events of neurons elicited by astrocytic glutamate via activation of extrasynaptic NMDA receptors. By using slice electrophysiology, we tried to provide evidence that SICs can elicit synaptic plasticity. Age dependence of SICs and their impact on s...

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Detalles Bibliográficos
Autores principales: Csemer, Andrea, Kovács, Adrienn, Maamrah, Baneen, Pocsai, Krisztina, Korpás, Kristóf, Klekner, Álmos, Szücs, Péter, Nánási, Péter P., Pál, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497838/
https://www.ncbi.nlm.nih.gov/pubmed/37489544
http://dx.doi.org/10.1111/acel.13939