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Fibroblast growth factor 10 ameliorates neurodegeneration in mouse and cellular models of Alzheimer's disease via reducing tau hyperphosphorylation and neuronal apoptosis

Alzheimer's disease (AD) is characterized with senile plaques formed by Aβ deposition, and neurofibrillary tangles composed of hyperphosphorylated tau protein, which ultimately lead to cognitive impairment. Despite the heavy economic and life burdens faced by the patients with AD, effective tre...

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Detalles Bibliográficos
Autores principales: Guo, Kaiming, Huang, Wenting, Chen, Kun, Huang, Pengkai, Peng, Wenshuo, Shi, Ruiqing, He, Tao, Zhang, Mulan, Wang, Hao, Hu, Jian, Wang, Xinshi, Shentu, Yangping, Xu, Huiqin, Lin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497839/
https://www.ncbi.nlm.nih.gov/pubmed/37503695
http://dx.doi.org/10.1111/acel.13937