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Glycogen phosphorylase inhibition improves cognitive function of aged mice

Inhibition of glycogen breakdown blocks memory formation in young animals, but it stimulates the maintenance of the long‐term potentiation, a cellular mechanism of memory formation, in hippocampal slices of old animals. Here, we report that a 2‐week treatment with glycogen phosphorylase inhibitor BA...

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Detalles Bibliográficos
Autores principales: Drulis‐Fajdasz, Dominika, Krzystyniak, Adam, Puścian, Alicja, Pytyś, Agata, Gostomska‐Pampuch, Kinga, Pudełko‐Malik, Natalia, Wiśniewski, Jerzy Ł., Młynarz, Piotr, Miazek, Arkadiusz, Wójtowicz, Tomasz, Włodarczyk, Jakub, Duś‐Szachniewicz, Kamila, Gizak, Agnieszka, Wiśniewski, Jacek R., Rakus, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497847/
https://www.ncbi.nlm.nih.gov/pubmed/37522798
http://dx.doi.org/10.1111/acel.13928