Dual-targeting peptides@PMO, a mimetic to the pro-apoptotic protein Smac/DIABLO for selective activation of apoptosis in cancer cells

The refractoriness of tumor cells to apoptosis represents the main mechanism of resistance to chemotherapy. Smac/DIABLO mimetics proved to be effective in overcoming cancer-acquired resistance to apoptosis as a consequence of overexpression of the anti-apoptotic proteins XIAP, cIAP1, and cIAP2. In t...

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Detalles Bibliográficos
Autores principales: Di Giorgio, Eros, Ferino, Annalisa, Huang, Weizhe, Simonetti, Sigrid, Xodo, Luigi, De Marco, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497945/
https://www.ncbi.nlm.nih.gov/pubmed/37711175
http://dx.doi.org/10.3389/fphar.2023.1237478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497945/
https://www.ncbi.nlm.nih.gov/pubmed/37711175
http://dx.doi.org/10.3389/fphar.2023.1237478

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