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Micro-simulation insights into the functional and mechanistic understanding of glycyrrhizin against asthma

Asthma is a common chronic respiratory disease, which causes inflammation and airway stenosis, leading to dyspnea, wheezing and chest tightness. Using transgelin-2 as a target, we virtually screened the lead compound glycyrrhizin from the self-built database of anti-asthma compounds by molecular doc...

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Detalles Bibliográficos
Autores principales: Qi, Jian-Hong, Xu, Dong-Chuan, Wang, Xiao-Long, Cai, Ding-Yuan, Wang, Yi, Zhou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497961/
https://www.ncbi.nlm.nih.gov/pubmed/37711178
http://dx.doi.org/10.3389/fphar.2023.1220368