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Uric acid regulates α-synuclein transmission in Parkinsonian models

Ample evidence demonstrates that α-synuclein (α-syn) has a critical role in the pathogenesis of Parkinson’s disease (PD) with evidence indicating that its propagation from one area of the brain to others may be the primary mechanism for disease progression. Uric acid (UA), a natural antioxidant, has...

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Detalles Bibliográficos
Autores principales: Shin, Yu Jin, Kim, Yeon Ju, Lee, Ji Eun, Kim, Yi Seul, Lee, Jung Wook, Kim, HyeonJeong, Shin, Jin Young, Lee, Phil Hyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497982/
https://www.ncbi.nlm.nih.gov/pubmed/37711993
http://dx.doi.org/10.3389/fnagi.2023.1117491