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Biomarker-based risk prediction for the onset of neuroinflammation in X-linked adrenoleukodystrophy

BACKGROUND: X-linked adrenoleukodystrophy (X-ALD) is highly variable, ranging from slowly progressive adrenomyeloneuropathy to severe brain demyelination and inflammation (cerebral ALD, CALD) affecting males with childhood peak onset. Risk models integrating blood-based biomarkers to indicate CALD o...

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Detalles Bibliográficos
Autores principales: Weinhofer, Isabelle, Rommer, Paulus, Gleiss, Andreas, Ponleitner, Markus, Zierfuss, Bettina, Waidhofer-Söllner, Petra, Fourcade, Stéphane, Grabmeier-Pfistershammer, Katharina, Reinert, Marie-Christine, Göpfert, Jens, Heine, Anne, Yska, Hemmo A.F., Casasnovas, Carlos, Cantarín, Verónica, Bergner, Caroline G., Mallack, Eric, Forss-Petter, Sonja, Aubourg, Patrick, Bley, Annette, Engelen, Marc, Eichler, Florian, Lund, Troy C., Pujol, Aurora, Köhler, Wolfgang, Kühl, Jörn-Sven, Berger, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497986/
https://www.ncbi.nlm.nih.gov/pubmed/37683329
http://dx.doi.org/10.1016/j.ebiom.2023.104781