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A half century of exploring DNA excision repair in chromatin

DNA in eukaryotic cells is packaged into the compact and dynamic structure of chromatin. This packaging is a double-edged sword for DNA repair and genomic stability. Chromatin restricts the access of repair proteins to DNA lesions embedded in nucleosomes and higher order chromatin structures. Howeve...

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Detalles Bibliográficos
Autores principales: Smerdon, Michael J., Wyrick, John J., Delaney, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498010/
https://www.ncbi.nlm.nih.gov/pubmed/37527775
http://dx.doi.org/10.1016/j.jbc.2023.105118