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Translation of biophysical environment in bone into dynamic cell culture under flow for bone tissue engineering

Bone is a dynamic environment where osteocytes, osteoblasts, and mesenchymal stem/progenitor cells perceive mechanical cues and regulate bone metabolism accordingly. In particular, interstitial fluid flow in bone and bone marrow serves as a primary biophysical stimulus, which regulates the growth an...

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Detalles Bibliográficos
Autores principales: Yamada, Shuntaro, Ockermann, Philipp Niklas, Schwarz, Thomas, Mustafa, Kamal, Hansmann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498129/
https://www.ncbi.nlm.nih.gov/pubmed/37711188
http://dx.doi.org/10.1016/j.csbj.2023.08.008