Design, green synthesis, and quorum sensing quenching potential of novel 2-oxo-pyridines containing a thiophene/furan scaffold and targeting a LasR gene on P. aeruginosa

The current trend in fighting bacteria is attacking the virulence and quorum-sensing (QS) signals that control bacterial communication and virulence factors, especially biofilm formation. This study reports new Schiff bases and tetracyclic rings based on a pyridine pharmacophore by two methods: a gr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ammar, Yousry A., Ragab, Ahmed, Migahed, M. A., Al-Sharbasy, S., Salem, Mohamed A., Riad, Omnia Karem M., Selim, Heba Mohammed Refat M., Abd-elmaksoud, Gehad A., Abusaif, Moustafa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498153/
https://www.ncbi.nlm.nih.gov/pubmed/37711372
http://dx.doi.org/10.1039/d3ra04230h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498153/
https://www.ncbi.nlm.nih.gov/pubmed/37711372
http://dx.doi.org/10.1039/d3ra04230h

Ejemplares similares