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Design, green synthesis, and quorum sensing quenching potential of novel 2-oxo-pyridines containing a thiophene/furan scaffold and targeting a LasR gene on P. aeruginosa
The current trend in fighting bacteria is attacking the virulence and quorum-sensing (QS) signals that control bacterial communication and virulence factors, especially biofilm formation. This study reports new Schiff bases and tetracyclic rings based on a pyridine pharmacophore by two methods: a gr...
Autores principales: | Ammar, Yousry A., Ragab, Ahmed, Migahed, M. A., Al-Sharbasy, S., Salem, Mohamed A., Riad, Omnia Karem M., Selim, Heba Mohammed Refat M., Abd-elmaksoud, Gehad A., Abusaif, Moustafa S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498153/ https://www.ncbi.nlm.nih.gov/pubmed/37711372 http://dx.doi.org/10.1039/d3ra04230h |
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