Hyperammonemia induces microglial NLRP3 inflammasome activation via mitochondrial oxidative stress in hepatic encephalopathy

BACKGROUND: The role of nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in the pathogenesis of hepatic encephalopathy (HE) is unclear. Mitochondrial reactive oxygen species (mtROS) is a signal for NLRP3 inflammasome activation. Therefore, we aimed to determine...

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Detalles Bibliográficos
Autores principales: Cheon, So Yeong, Kim, Min-Yu, Kim, Jeongmin, Kim, Eun Jung, Kam, Eun Hee, Cho, Inja, Koo, Bon-Nyeo, Kim, So Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498413/
https://www.ncbi.nlm.nih.gov/pubmed/37059364
http://dx.doi.org/10.1016/j.bj.2023.04.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498413/
https://www.ncbi.nlm.nih.gov/pubmed/37059364
http://dx.doi.org/10.1016/j.bj.2023.04.001

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