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Targeted Protein Degradation: Advances, Challenges, and Prospects for Computational Methods

[Image: see text] The therapeutic approach of targeted protein degradation (TPD) is gaining momentum due to its potentially superior effects compared with protein inhibition. Recent advancements in the biotech and pharmaceutical sectors have led to the development of compounds that are currently in...

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Detalles Bibliográficos
Autores principales: Mostofian, Barmak, Martin, Holli-Joi, Razavi, Asghar, Patel, Shivam, Allen, Bryce, Sherman, Woody, Izaguirre, Jesus A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498452/
https://www.ncbi.nlm.nih.gov/pubmed/37602861
http://dx.doi.org/10.1021/acs.jcim.3c00603