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Dendritic cell-based vaccine prepared with recombinant Lactococcus lactis enhances antigen cross-presentation and antitumor efficacy through ROS production

INTRODUCTION: Lactococcus lactis (L.L) is safe and can be used as vehicle. In this study, the immunoregulatory effect of L.L on dendritic cell (DC) activation and mechanism were investigated. The immune responses and antigen cross-presentation mechanism of DC-based vaccine prepared with OVA recombin...

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Detalles Bibliográficos
Autores principales: Zhang, Tingting, Wei, Xianxian, Li, Yijie, Huang, Shuai, Wu, Yulin, Cai, Shanshan, Aipire, Adila, Li, Jinyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498461/
https://www.ncbi.nlm.nih.gov/pubmed/37711617
http://dx.doi.org/10.3389/fimmu.2023.1208349