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Neuroprotection by upregulation of the major histocompatibility complex class I (MHC I) in SOD1(G93A) mice
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that progressively affects motoneurons, causing muscle atrophy and evolving to death. Astrocytes inhibit the expression of MHC-I by neurons, contributing to a degenerative outcome. The present study verified the influence of interfer...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498468/ https://www.ncbi.nlm.nih.gov/pubmed/37711512 http://dx.doi.org/10.3389/fncel.2023.1211486 |