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Neuroprotection by upregulation of the major histocompatibility complex class I (MHC I) in SOD1(G93A) mice

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that progressively affects motoneurons, causing muscle atrophy and evolving to death. Astrocytes inhibit the expression of MHC-I by neurons, contributing to a degenerative outcome. The present study verified the influence of interfer...

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Detalles Bibliográficos
Autores principales: Tomiyama, Ana Laura M. R., Cartarozzi, Luciana Politti, de Oliveira Coser, Lilian, Chiarotto, Gabriela Bortolança, Oliveira, Alexandre L. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498468/
https://www.ncbi.nlm.nih.gov/pubmed/37711512
http://dx.doi.org/10.3389/fncel.2023.1211486