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Collaborative SAR Modeling and Prospective In Vitro Validation of Oxidative Stress Activation in Human HepG2 Cells

[Image: see text] Oxidative stress is the consequence of an abnormal increase of reactive oxygen species (ROS). ROS are generated mainly during the metabolism in both normal and pathological conditions as well as from exposure to xenobiotics. Xenobiotics can, on the one hand, disrupt molecular machi...

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Detalles Bibliográficos
Autores principales: Béquignon, Olivier J. M., Gómez-Tamayo, Jose C., Lenselink, Eelke B., Wink, Steven, Hiemstra, Steven, Lam, Chi Chung, Gadaleta, Domenico, Roncaglioni, Alessandra, Norinder, Ulf, Water, Bob van de, Pastor, Manuel, van Westen, Gerard J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498489/
https://www.ncbi.nlm.nih.gov/pubmed/37616385
http://dx.doi.org/10.1021/acs.jcim.3c00220