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Bacterial lipopolysaccharide-induced endothelial activation and dysfunction: a new predictive and therapeutic paradigm for sepsis

BACKGROUND: Lipopolysaccharide, a highly potent endotoxin responsible for severe sepsis, is the major constituent of the outer membrane of gram-negative bacteria. Endothelial cells participate in both innate and adaptive immune responses as the first cell types to detect lipopolysaccharide or other...

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Detalles Bibliográficos
Autores principales: Wang, Min, Feng, Jun, Zhou, Daixing, Wang, Junshuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498524/
https://www.ncbi.nlm.nih.gov/pubmed/37700349
http://dx.doi.org/10.1186/s40001-023-01301-5