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Sin3a associated protein 130 kDa, sap130, plays an evolutionary conserved role in zebrafish heart development
Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where the left ventricle is reduced in size. A forward genetic screen in mice identified SIN3A associated protein 130 kDa (Sap130), part of the chromatin modifying SIN3A/HDAC complex, as a gene contributing to the etiology of HLHS....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498550/ https://www.ncbi.nlm.nih.gov/pubmed/37711853 http://dx.doi.org/10.3389/fcell.2023.1197109 |