Cargando…

Sin3a associated protein 130 kDa, sap130, plays an evolutionary conserved role in zebrafish heart development

Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where the left ventricle is reduced in size. A forward genetic screen in mice identified SIN3A associated protein 130 kDa (Sap130), part of the chromatin modifying SIN3A/HDAC complex, as a gene contributing to the etiology of HLHS....

Descripción completa

Detalles Bibliográficos
Autores principales: DeMoya, Ricardo A., Forman-Rubinsky, Rachel E., Fontaine, Deon, Shin, Joseph, Watkins, Simon C., Lo, Cecilia W., Tsang, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498550/
https://www.ncbi.nlm.nih.gov/pubmed/37711853
http://dx.doi.org/10.3389/fcell.2023.1197109