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N-acetylglucosamine inhibits inflammation and neurodegeneration markers in multiple sclerosis: a mechanistic trial

BACKGROUND: In the demyelinating disease multiple sclerosis (MS), chronic-active brain inflammation, remyelination failure and neurodegeneration remain major issues despite immunotherapy. While B cell depletion and blockade/sequestration of T and B cells potently reduces episodic relapses, they act...

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Detalles Bibliográficos
Autores principales: Sy, Michael, Newton, Barbara L., Pawling, Judy, Hayama, Ken L., Cordon, Andres, Yu, Zhaoxia, Kuhle, Jens, Dennis, James W., Brandt, Alexander U., Demetriou, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498575/
https://www.ncbi.nlm.nih.gov/pubmed/37705084
http://dx.doi.org/10.1186/s12974-023-02893-9