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Human NCR3 gene variants rs2736191 and rs11575837 alter longitudinal risk for development of pediatric malaria episodes and severe malarial anemia

BACKGROUND: Plasmodium falciparum malaria is a leading cause of pediatric morbidity and mortality in holoendemic transmission areas. Severe malarial anemia [SMA, hemoglobin (Hb) < 5.0 g/dL in children] is the most common clinical manifestation of severe malaria in such regions. Although innate im...

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Detalles Bibliográficos
Autores principales: Onyango, Clinton O., Cheng, Qiuying, Munde, Elly O., Raballah, Evans, Anyona, Samuel B., McMahon, Benjamin H., Lambert, Christophe G., Onyango, Patrick O., Schneider, Kristan A., Perkins, Douglas J., Ouma, Collins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498606/
https://www.ncbi.nlm.nih.gov/pubmed/37704951
http://dx.doi.org/10.1186/s12864-023-09565-1