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Modelling porcine NAFLD by deletion of leptin and defining the role of AMPK in hepatic fibrosis

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic hepatic disease and results in non-alcoholic steatohepatitis (NASH), which progresses to fibrosis and cirrhosis. Although the Leptin deficient rodent models are widely used in study of metabolic syndrome and...

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Detalles Bibliográficos
Autores principales: Tan, Tan, Song, Zhiyuan, Li, Wenya, Wang, Runming, Zhu, Mingli, Liang, Zuoxiang, Bai, Yilina, Wang, Qi, Wu, Hanyu, Hu, Xiaoxiang, Xing, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498639/
https://www.ncbi.nlm.nih.gov/pubmed/37705071
http://dx.doi.org/10.1186/s13578-023-01124-1