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Modelling porcine NAFLD by deletion of leptin and defining the role of AMPK in hepatic fibrosis
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic hepatic disease and results in non-alcoholic steatohepatitis (NASH), which progresses to fibrosis and cirrhosis. Although the Leptin deficient rodent models are widely used in study of metabolic syndrome and...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498639/ https://www.ncbi.nlm.nih.gov/pubmed/37705071 http://dx.doi.org/10.1186/s13578-023-01124-1 |