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Multicomponent reaction (MCR) for constructing bis-spirocyclohexane skeletons using β-nitrostyrene derived MBH acetates, 1,3-indanedione and aldehydes via [1 + 1 + 1 + 3] annulation

An AB(2)C type four-component quadruple cascade reaction has been established between nitroallylic MBH acetate, 1,3-indanedione and aldehyde for generating bis-spirocyclohexanes. This reaction progressed in an unusual [1 + 1 + 1 + 3] annulation manner via a Knoevenagel/Michael/Michael/Michael sequen...

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Detalles Bibliográficos
Autores principales: Gudise, Veera Babu, Anwar, Shaik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498677/
https://www.ncbi.nlm.nih.gov/pubmed/37711377
http://dx.doi.org/10.1039/d3ra04996e