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Bone destruction in chronic otitis media is not mediated by the RANKL pathway or estrogen receptor-alpha

BACKGROUND: Chronic otitis media with or without cholesteatoma progresses with various degrees of bone resorption and remodeling. Estrogen mediates osteoprotective effects through the receptor activator of NF-κB ligand (RANKL) pathway, which is mainly mediated by estrogen receptor-alpha (ER-α). OBJE...

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Detalles Bibliográficos
Autores principales: Heo, Kyung Wook, Noh, MinHye, Hur, Dae Young, Hong, Tae Ui, Park, Sung Yool, Kim, Woo Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498706/
https://www.ncbi.nlm.nih.gov/pubmed/37697808
http://dx.doi.org/10.1177/00368504231199204