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Trophoblast organoids with physiological polarity model placental structure and function

Human trophoblast organoids (TOs) are a three-dimensional ex vivo culture model that can be used to study various aspects of placental development, physiology and pathology. However, standard culturing of TOs does not recapitulate the cellular orientation of chorionic villi in vivo given that the mu...

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Detalles Bibliográficos
Autores principales: Yang, Liheng, Liang, Pengfei, Yang, Huanghe, Coyne, Carolyn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499031/
https://www.ncbi.nlm.nih.gov/pubmed/37676312
http://dx.doi.org/10.1242/jcs.261528