Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins

In mammalian cells, misfolded glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) are cleared out of the ER to the Golgi via a constitutive and a stress-inducible pathway called RESET. From the Golgi, misfolded GPI-APs transiently access the cell surface prior to rapid internalization for...

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Detalles Bibliográficos
Autores principales: Cheatham, Amber M., Sharma, Nishi Raj, Satpute-Krishnan, Prasanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499038/
https://www.ncbi.nlm.nih.gov/pubmed/37702712
http://dx.doi.org/10.1083/jcb.202108160

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