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The microbiota conditions a gut milieu that selects for wild-type Salmonella Typhimurium virulence

Salmonella Typhimurium elicits gut inflammation by the costly expression of HilD-controlled virulence factors. This inflammation alleviates colonization resistance (CR) mediated by the microbiota and thereby promotes pathogen blooms. However, the inflamed gut-milieu can also select for hilD mutants,...

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Detalles Bibliográficos
Autores principales: Gül, Ersin, Bakkeren, Erik, Salazar, Guillem, Steiger, Yves, Abi Younes, Andrew, Clerc, Melanie, Christen, Philipp, Fattinger, Stefan A., Nguyen, Bidong D., Kiefer, Patrick, Slack, Emma, Ackermann, Martin, Vorholt, Julia A., Sunagawa, Shinichi, Diard, Médéric, Hardt, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499267/
https://www.ncbi.nlm.nih.gov/pubmed/37651408
http://dx.doi.org/10.1371/journal.pbio.3002253