Chimeric hemagglutinin split vaccines elicit broadly cross-reactive antibodies and protection against group 2 influenza viruses in mice

Seasonal influenza virus vaccines are effective when they are well matched to circulating strains. Because of antigenic drift/change in the immunodominant hemagglutinin (HA) head domain, annual vaccine reformulations are necessary to maintain a match with circulating strains. In addition, seasonal v...

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Detalles Bibliográficos
Autores principales: Puente-Massaguer, Eduard, Vasilev, Kirill, Beyer, Annika, Loganathan, Madhumathi, Francis, Benjamin, Scherm, Michael J., Arunkumar, Guha Asthagiri, González-Domínguez, Irene, Zhu, Xueyong, Wilson, Ian A., Coughlan, Lynda, Sun, Weina, Palese, Peter, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499326/
https://www.ncbi.nlm.nih.gov/pubmed/37703367
http://dx.doi.org/10.1126/sciadv.adi4753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499326/
https://www.ncbi.nlm.nih.gov/pubmed/37703367
http://dx.doi.org/10.1126/sciadv.adi4753

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