Epitope editing enables targeted immunotherapy of acute myeloid leukaemia

Despite the considerable efficacy observed when targeting a dispensable lineage antigen, such as CD19 in B cell acute lymphoblastic leukaemia(1,2), the broader applicability of adoptive immunotherapies is hampered by the absence of tumour-restricted antigens(3–5). Acute myeloid leukaemia immunothera...

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Detalles Bibliográficos
Autores principales: Casirati, Gabriele, Cosentino, Andrea, Mucci, Adele, Salah Mahmoud, Mohammed, Ugarte Zabala, Iratxe, Zeng, Jing, Ficarro, Scott B., Klatt, Denise, Brendel, Christian, Rambaldi, Alessandro, Ritz, Jerome, Marto, Jarrod A., Pellin, Danilo, Bauer, Daniel E., Armstrong, Scott A., Genovese, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499609/
https://www.ncbi.nlm.nih.gov/pubmed/37648862
http://dx.doi.org/10.1038/s41586-023-06496-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499609/
https://www.ncbi.nlm.nih.gov/pubmed/37648862
http://dx.doi.org/10.1038/s41586-023-06496-5

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