Single-cell brain organoid screening identifies developmental defects in autism

The development of the human brain involves unique processes (not observed in many other species) that can contribute to neurodevelopmental disorders(1–4). Cerebral organoids enable the study of neurodevelopmental disorders in a human context. We have developed the CRISPR–human organoids–single-cell...

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Detalles Bibliográficos
Autores principales: Li, Chong, Fleck, Jonas Simon, Martins-Costa, Catarina, Burkard, Thomas R., Themann, Jan, Stuempflen, Marlene, Peer, Angela Maria, Vertesy, Ábel, Littleboy, Jamie B., Esk, Christopher, Elling, Ulrich, Kasprian, Gregor, Corsini, Nina S., Treutlein, Barbara, Knoblich, Juergen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499611/
https://www.ncbi.nlm.nih.gov/pubmed/37704762
http://dx.doi.org/10.1038/s41586-023-06473-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499611/
https://www.ncbi.nlm.nih.gov/pubmed/37704762
http://dx.doi.org/10.1038/s41586-023-06473-y

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