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Chronic stress induces meiotic arrest failure and ovarian reserve decline via the cAMP signaling pathway

Chronic stress is suspected to be a causal factor of female subfertility; however, the underlying mechanisms remain unclear. Here, we found that chronic stress inhibited the cyclic adenosine 3′,5′-monophosphate (cAMP) signaling pathway, leading to ovarian reserve decline in mice. A chronic stress mo...

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Detalles Bibliográficos
Autores principales: Jiang, Yiwen, Xu, Jing, Tao, Chengqiu, Lin, Yunying, Lin, Xiaoqi, Li, Ke, Liu, Qiyu, Saiyin, Hexige, Hu, Shuanggang, Yao, Guangxin, Sun, Yun, Zhang, Feng, Kang, Yu, Xu, Congjian, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499613/
https://www.ncbi.nlm.nih.gov/pubmed/37720535
http://dx.doi.org/10.3389/fendo.2023.1177061