Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model

BACKGROUND, OBJECTIVES AND DESIGN: Arachidonic acid 15-lipoxygenase (ALOX15) has been implicated in the pathogenesis of inflammatory diseases but since pro- and anti-inflammatory roles have been suggested, the precise function of this enzyme is still a matter of discussion. To contribute to this dis...

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Detalles Bibliográficos
Autores principales: Heydeck, Dagmar, Kakularam, Kumar R., Labuz, Dominika, Machelska, Halina, Rohwer, Nadine, Weylandt, Karsten, Kuhn, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499711/
https://www.ncbi.nlm.nih.gov/pubmed/37498393
http://dx.doi.org/10.1007/s00011-023-01770-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499711/
https://www.ncbi.nlm.nih.gov/pubmed/37498393
http://dx.doi.org/10.1007/s00011-023-01770-8

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