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Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model
BACKGROUND, OBJECTIVES AND DESIGN: Arachidonic acid 15-lipoxygenase (ALOX15) has been implicated in the pathogenesis of inflammatory diseases but since pro- and anti-inflammatory roles have been suggested, the precise function of this enzyme is still a matter of discussion. To contribute to this dis...
Autores principales: | Heydeck, Dagmar, Kakularam, Kumar R., Labuz, Dominika, Machelska, Halina, Rohwer, Nadine, Weylandt, Karsten, Kuhn, Hartmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499711/ https://www.ncbi.nlm.nih.gov/pubmed/37498393 http://dx.doi.org/10.1007/s00011-023-01770-8 |
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