Neutrophils in STAT1 Gain-Of-Function Have a Pro-inflammatory Signature Which Is Not Rescued by JAK Inhibition

STAT1 gain-of-function (GOF) mutations cause an inborn error of immunity with diverse phenotype ranging from chronic mucocutaneous candidiasis (CMC) to various non-infectious manifestations, the most precarious of which are autoimmunity and vascular complications. The pathogenesis centers around Th1...

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Detalles Bibliográficos
Autores principales: Parackova, Zuzana, Vrabcova, Petra, Zentsova, Irena, Sediva, Anna, Bloomfield, Marketa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499747/
https://www.ncbi.nlm.nih.gov/pubmed/37358695
http://dx.doi.org/10.1007/s10875-023-01528-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499747/
https://www.ncbi.nlm.nih.gov/pubmed/37358695
http://dx.doi.org/10.1007/s10875-023-01528-1

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