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Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study

BACKGROUND: A neuroimaging-based biomarker termed the brain age is thought to reflect variability in the brain's ageing process and predict longevity. Using Insight 46, a unique narrow-age birth cohort, we aimed to examine potential drivers and correlates of brain age. METHODS: Participants, bo...

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Detalles Bibliográficos
Autores principales: Wagen, Aaron Z, Coath, William, Keshavan, Ashvini, James, Sarah-Naomi, Parker, Thomas D, Lane, Christopher A, Buchanan, Sarah M, Keuss, Sarah E, Storey, Mathew, Lu, Kirsty, Macdougall, Amy, Murray-Smith, Heidi, Freiberger, Tamar, Cash, David M, Malone, Ian B, Barnes, Josephine, Sudre, Carole H, Wong, Andrew, Pavisic, Ivanna M, Street, Rebecca, Crutch, Sebastian J, Escott-Price, Valentina, Leonenko, Ganna, Zetterberg, Henrik, Wellington, Henrietta, Heslegrave, Amanda, Barkhof, Frederik, Richards, Marcus, Fox, Nick C, Cole, James H, Schott, Jonathan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499760/
https://www.ncbi.nlm.nih.gov/pubmed/36102775
http://dx.doi.org/10.1016/S2666-7568(22)00167-2