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Optimization and characterization of antileukemic l-asparaginase produced by Fusarium solani endophyte

l-asparaginase is an antileukemic enzyme that hydrolyzes l-asparagine into l-aspartic acid and ammonia, causing cell starvation and apoptosis in susceptible leukemic cell populations. Currently, l-asparaginase obtained from bacterial sources is constrained by several issues, including lesser product...

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Detalles Bibliográficos
Autores principales: Osama, Sarah, El-Sherei, Moshera M., Al-Mahdy, Dalia A., Bishr, Mokhtar, Salama, Osama, Raafat, Marwa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499768/
https://www.ncbi.nlm.nih.gov/pubmed/37702815
http://dx.doi.org/10.1186/s13568-023-01602-2