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Disrupting iron homeostasis can potentiate colistin activity and overcome colistin resistance mechanisms in Gram-Negative Bacteria

Acinetobacter baumannii is a Gram-negative priority pathogen that can readily overcome antibiotic treatment through a range of intrinsic and acquired resistance mechanisms. Treatment of carbapenem-resistant A. baumannii largely relies on the use of colistin in cases where other treatment options hav...

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Detalles Bibliográficos
Autores principales: Gadar, Kavita, de Dios, Rubén, Kadeřábková, Nikol, Prescott, Thomas A. K., Mavridou, Despoina A. I., McCarthy, Ronan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499790/
https://www.ncbi.nlm.nih.gov/pubmed/37704838
http://dx.doi.org/10.1038/s42003-023-05302-2