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Disrupting iron homeostasis can potentiate colistin activity and overcome colistin resistance mechanisms in Gram-Negative Bacteria
Acinetobacter baumannii is a Gram-negative priority pathogen that can readily overcome antibiotic treatment through a range of intrinsic and acquired resistance mechanisms. Treatment of carbapenem-resistant A. baumannii largely relies on the use of colistin in cases where other treatment options hav...
Autores principales: | Gadar, Kavita, de Dios, Rubén, Kadeřábková, Nikol, Prescott, Thomas A. K., Mavridou, Despoina A. I., McCarthy, Ronan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499790/ https://www.ncbi.nlm.nih.gov/pubmed/37704838 http://dx.doi.org/10.1038/s42003-023-05302-2 |
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