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CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer´s disease

Diagnosis of dementia with Lewy bodies (DLB) is challenging and specific biofluid biomarkers are highly needed. We employed proximity extension-based assays to measure 665 proteins in the cerebrospinal fluid (CSF) from patients with DLB (n = 109), Alzheimer´s disease (AD, n = 235) and cognitively un...

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Detalles Bibliográficos
Autores principales: del Campo, Marta, Vermunt, Lisa, Peeters, Carel F. W., Sieben, Anne, Hok-A-Hin, Yanaika S., Lleó, Alberto, Alcolea, Daniel, van Nee, Mirrelijn, Engelborghs, Sebastiaan, van Alphen, Juliette L., Arezoumandan, Sanaz, Chen-Plotkin, Alice, Irwin, David J., van der Flier, Wiesje M., Lemstra, Afina W., Teunissen, Charlotte E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499811/
https://www.ncbi.nlm.nih.gov/pubmed/37704597
http://dx.doi.org/10.1038/s41467-023-41122-y