Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment

The translocation t(1;19)(q23;p13) with the resulting chimeric TCF3::PBX1 gene is the third most prevalent recurrent chromosomal translocation in acute lymphoblastic leukemia and accounts for 3–5% of cases. The molecular background of this translocation has been incompletely studied, especially in a...

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Detalles Bibliográficos
Autores principales: Burmeister, Thomas, Gröger, Daniela, Gökbuget, Nicola, Spriewald, Bernd, Starck, Michael, Elmaagacli, Ahmet, Hoelzer, Dieter, Keller, Ulrich, Schwartz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499895/
https://www.ncbi.nlm.nih.gov/pubmed/37704696
http://dx.doi.org/10.1038/s41598-023-42294-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499895/
https://www.ncbi.nlm.nih.gov/pubmed/37704696
http://dx.doi.org/10.1038/s41598-023-42294-9

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