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HMGB2 regulates the differentiation and stemness of exhausted CD8(+) T cells during chronic viral infection and cancer
Chronic infections and cancers evade the host immune system through mechanisms that induce T cell exhaustion. The heterogeneity within the exhausted CD8(+) T cell pool has revealed the importance of stem-like progenitor (Tpex) and terminal (Tex) exhausted T cells, although the mechanisms underlying...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499904/ https://www.ncbi.nlm.nih.gov/pubmed/37704621 http://dx.doi.org/10.1038/s41467-023-41352-0 |