Cargando…

HMGB2 regulates the differentiation and stemness of exhausted CD8(+) T cells during chronic viral infection and cancer

Chronic infections and cancers evade the host immune system through mechanisms that induce T cell exhaustion. The heterogeneity within the exhausted CD8(+) T cell pool has revealed the importance of stem-like progenitor (Tpex) and terminal (Tex) exhausted T cells, although the mechanisms underlying...

Descripción completa

Detalles Bibliográficos
Autores principales: Neubert, Emily N., DeRogatis, Julia M., Lewis, Sloan A., Viramontes, Karla M., Ortega, Pedro, Henriquez, Monique L., Buisson, Rémi, Messaoudi, Ilhem, Tinoco, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499904/
https://www.ncbi.nlm.nih.gov/pubmed/37704621
http://dx.doi.org/10.1038/s41467-023-41352-0