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Structural and biological characterization of shortened derivatives of the cathelicidin PMAP-36

Cathelicidins, a family of host defence peptides in vertebrates, play an important role in the innate immune response, exhibiting antimicrobial activity against many bacteria, as well as viruses and fungi. This work describes the design and synthesis of shortened analogues of porcine cathelicidin PM...

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Detalles Bibliográficos
Autores principales: Biondi, Barbara, de Pascale, Luigi, Mardirossian, Mario, Di Stasi, Adriana, Favaro, Matteo, Scocchi, Marco, Peggion, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499915/
https://www.ncbi.nlm.nih.gov/pubmed/37704689
http://dx.doi.org/10.1038/s41598-023-41945-1