Deep spatial-omics analysis of Head & Neck carcinomas provides alternative therapeutic targets and rationale for treatment failure

Immune checkpoint inhibitor (ICI) therapy has had limited success (<30%) in treating metastatic recurrent Head and Neck Oropharyngeal Squamous Cell Carcinomas (OPSCCs). We postulate that spatial determinants in the tumor play a critical role in cancer therapy outcomes. Here, we describe the case...

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Detalles Bibliográficos
Autores principales: Causer, Andrew, Tan, Xiao, Lu, Xuehan, Moseley, Philip, Teoh, Siok M., Molotkov, Natalie, McGrath, Margaret, Kim, Taehyun, Simpson, Peter T., Perry, Christopher, Frazer, Ian H., Panizza, Benedict, Ladwa, Rahul, Nguyen, Quan, Gonzalez-Cruz, Jazmina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499928/
https://www.ncbi.nlm.nih.gov/pubmed/37704757
http://dx.doi.org/10.1038/s41698-023-00444-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499928/
https://www.ncbi.nlm.nih.gov/pubmed/37704757
http://dx.doi.org/10.1038/s41698-023-00444-2

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