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The context-dependent role of the Na(+)/Ca(2+)-exchanger (NCX) in pancreatic stellate cell migration

Pancreatic stellate cells (PSCs) that can co-metastasize with cancer cells shape the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) by producing an excessive amount of extracellular matrix. This leads to a TME characterized by increased tissue pressure, hypoxia, and acidity....

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Detalles Bibliográficos
Autores principales: Loeck, Thorsten, Rugi, Micol, Todesca, Luca Matteo, Kalinowska, Paulina, Soret, Benjamin, Neumann, Ilka, Schimmelpfennig, Sandra, Najder, Karolina, Pethő, Zoltán, Farfariello, Valerio, Prevarskaya, Natalia, Schwab, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499968/
https://www.ncbi.nlm.nih.gov/pubmed/37566113
http://dx.doi.org/10.1007/s00424-023-02847-3