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The context-dependent role of the Na(+)/Ca(2+)-exchanger (NCX) in pancreatic stellate cell migration
Pancreatic stellate cells (PSCs) that can co-metastasize with cancer cells shape the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) by producing an excessive amount of extracellular matrix. This leads to a TME characterized by increased tissue pressure, hypoxia, and acidity....
Autores principales: | Loeck, Thorsten, Rugi, Micol, Todesca, Luca Matteo, Kalinowska, Paulina, Soret, Benjamin, Neumann, Ilka, Schimmelpfennig, Sandra, Najder, Karolina, Pethő, Zoltán, Farfariello, Valerio, Prevarskaya, Natalia, Schwab, Albrecht |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499968/ https://www.ncbi.nlm.nih.gov/pubmed/37566113 http://dx.doi.org/10.1007/s00424-023-02847-3 |
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