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Ulinastatin ameliorated streptozotocin-induced diabetic nephropathy: Potential effects via modulating the components of gut-kidney axis and restoring mitochondrial homeostasis

Growing evidence supports the role of the gut-kidney axis and persistent mitochondrial dysfunction in the pathogenesis of diabetic nephropathy (DN). Ulinastatin (UTI) has a potent anti-inflammatory effect, protecting the kidney and the gut barrier in sepsis, but its effect on DN has yet to be invest...

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Detalles Bibliográficos
Autores principales: Rizk, Fatma H., El Saadany, Amira A., Atef, Marwa Mohamed, Abd-Ellatif, Rania Nagi, El-Guindy, Dina M., Abdel Ghafar, Muhammad T., Shalaby, Marwa M., Hafez, Yasser Mostafa, Mashal, Shaimaa Samir Amin, Basha, Eman H., Faheem, Heba, Barhoma, Ramez Abd-Elmoneim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499971/
https://www.ncbi.nlm.nih.gov/pubmed/37561129
http://dx.doi.org/10.1007/s00424-023-02844-6