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Ulinastatin ameliorated streptozotocin-induced diabetic nephropathy: Potential effects via modulating the components of gut-kidney axis and restoring mitochondrial homeostasis
Growing evidence supports the role of the gut-kidney axis and persistent mitochondrial dysfunction in the pathogenesis of diabetic nephropathy (DN). Ulinastatin (UTI) has a potent anti-inflammatory effect, protecting the kidney and the gut barrier in sepsis, but its effect on DN has yet to be invest...
Autores principales: | Rizk, Fatma H., El Saadany, Amira A., Atef, Marwa Mohamed, Abd-Ellatif, Rania Nagi, El-Guindy, Dina M., Abdel Ghafar, Muhammad T., Shalaby, Marwa M., Hafez, Yasser Mostafa, Mashal, Shaimaa Samir Amin, Basha, Eman H., Faheem, Heba, Barhoma, Ramez Abd-Elmoneim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499971/ https://www.ncbi.nlm.nih.gov/pubmed/37561129 http://dx.doi.org/10.1007/s00424-023-02844-6 |
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